Citation

Bagmetova VV, Krivitskaya AN, Tyurenkov IN. Bull. Exp. Biol. Med. 2015; 159(1): 48-52.

Affiliation

Volgograd State Medical University, Ministry of Health of the Russian Federation, Volgograd, Russia, vvbagmetova@gmail.com.

Copyright

(Copyright © 2015, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s10517-015-2887-8

PMID

26033589

Abstract

Anti-aggressive effects of phenibut (25 mg/kg) and its structural analogue citrocard (50 mg/kg) were revealed in rats under condition of provoked intraspecific aggression. These substances significantly decreased manifestations of aggression in animals: they increased the latency of attacks and reduced their number. Anti-aggressive effects of citrocard were more pronounced than effects of phenibut under conditions of non-competitive aggression induced by fear of inescapable painful exposure or under conditions of competitive aggression reflecting the ability of animals to reveal adaptive social communicative skills in aversive situation.

Language: en