Citation

Dhital R, Norman I, Whittlesea C, Murrells T, McCambridge J. Addiction 2015; 110(10): 1586-1594.

Affiliation

Mental Health & Addictions Research Group, Department of Health Sciences, Faculty of Science, University of York, Heslington, UK.

Copyright

(Copyright © 2015, John Wiley and Sons)

DOI

10.1111/add.12994

PMID

25988589

Abstract

BACKGROUND & AIMS: To undertake the first randomised controlled trial to evaluate the effectiveness of a brief intervention delivered by community pharmacists to reduce hazardous or harmful drinking.

DESIGN: This parallel group individually randomised trial, allocated participants to brief alcohol intervention (n = 205) or a leaflet-only control condition (n = 202), with follow-up study after 3 months. SETTING: 16 community pharmacies in one London borough, UK. PARTICIPANTS: 407 pharmacy customers (aged 18 or over) with AUDIT scores 8-19 inclusive. INTERVENTION: A brief motivational discussion of approximately 10 minutes duration for which 17 pharmacists received a half-day of training. MEASUREMENTS: Hazardous or harmful drinking was assessed using the Alcohol Use Disorders Identification Test (AUDIT) administered by telephone by a researcher blind to allocation status. The two primary outcomes were: 1) change in AUDIT total scores and 2) the proportions no longer hazardous or harmful drinkers (scoring <8) at three months. The four secondary outcomes were: the three sub-scale scores of the AUDIT (for consumption, problems and dependence), and health status according to the EQ-5D (a standardised instrument for use as a measure of health outcome).

FINDINGS: At 3 months 326 (80% overall; 82% intervention, 78% control) participants were followed up. The difference in reduction in total AUDIT score (intervention minus control) was -0.57 95% CI -1.59 to 0.45, p = 0.28. The odds ratio for AUDIT <8 (control as reference) was 0.87 95% CI 0.50 to 1.51, p = 0.61). For two of the four secondary outcomes (dependence score: -0.46 95% CI -0.82 to -0.09, p = 0.014; health status score: -0.09 95% CI -0.16 to -0.02, p = 0.013) the control group did better, and in the other two there were no differences (consumption score: -0.05 95% CI -0.54 to 0.44, p = 0.85; non-dependence problems score: -0.13 95% CI -0.66 to 0.41). Sensitivity analyses did not change these findings.

CONCLUSIONS: A brief intervention delivered by community pharmacists appears to have had no effect in reducing hazardous or harmful alcohol consumption. This article is protected by copyright. All rights reserved.

Language: en