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Citation
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Ahmadpanah M, Haghighi M, Jahangard L, Borzoei S, Heshmati S, Bajoghli H, Holsboer-Trachsler E, Brand S. Int. J. Psychiatry Clin. Prac. 2015; 19(3): 168-173. |
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Abstract
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OBJECTIVES: The aim of the present study was to provide further evidence of 1) metabolic syndrome and blood lipids differences between suicide attempting and non-attempting patients with bipolar I disorder (BPD) and 2) as a function of acute depressive or manic phase.
METHODS: Fifty inpatients (mean age: 36.14: 48% males) with bipolar I disorder took part in the study. After recruitment, patients were clustered in four groups: 13 suicide attempters (SAs) assessed during a manic phase, 12 SAs assessed during a depressive phase; 15 non-SAs assessed during a manic phase, and 10 non-SAs assessed during a depressive phase. BMI, metabolic syndrome, blood pressure, blood lipids (cholesterol, high- und low-density lipids, triglyceride), and fasting blood sugar were assessed.
RESULTS: Neither metabolic syndrome, blood lipid values, fasting blood sugar, nor BMI or blood pressure differed between the SAs and non-SAs, or between patients in an acute manic phase and those in a depressed phase. The overall prevalence of metabolic syndrome was 26.0%.
CONCLUSION: Among patients with BPD I neither the occurrence of metabolic syndrome, nor lipid values or fasting blood sugar are reliable biomarkers of suicidal behavior during either acute depressive or manic phases.
Language: en |