Citation

Agrawal VK, Bansal A, Singh RK, Kumawat BL, Mahajan P. Indian J. Crit. Care Med. 2015; 19(2): 109-112.

Affiliation

Department of Critical Care Medicine and Pulmonology, Metro Heart Institute with Multispeciality, Sector 16A, Faridabad, Haryana, India.

Copyright

(Copyright © 2015, Indian Society of Critical Care Medicine, Publisher Medknow Publications)

DOI

10.4103/0972-5229.151019

PMID

25722553

PMCID

PMC4339895

Abstract

Aluminum phosphide (ALP) poisoning is one of the major causes of suicidal deaths. Toxicity by ALP is caused by the liberation of phosphine gas, which rapidly causes cell hypoxia due to inhibition of oxidative phosphorylation, leading to circulatory failure. Treatment of ALP toxicity is mainly supportive as there is no specific antidote. We recently managed 7 cases of ALP poisoning with severe hemodynamic effects. Patients were treated with supportive measures including gastric lavage with diluted potassium permanganate, coconut oil and sodium-bicarbonate first person account should be avoided in a scientific paper. Intravenous magnesium sulfate, proper hemodynamic monitoring and vasopressors. Four out of 7 survived thus suggesting a role of such supportive measures in the absence of specific antidote for ALP poisoning.

Language: en