Citation

McMillen BA, DaVanzo EA, Song AH, Scott SM, Rodriguez ME. Eur. J. Pharmacol. 1989; 160(1): 149-153.

Affiliation

Department of Pharmacology, School of Medicine, East Carolina University, Greenville, NC 27858.

Copyright

(Copyright © 1989, Elsevier Publishing)

DOI

unavailable

PMID

2565815

Abstract

A series of classical, atypical and putative antipsychotic drugs were compared for their ability to inhibit isolation-induced intraspecies aggression with affinity for D-2 dopamine receptors and induction of akinesia. The majority of drugs tested significantly inhibited aggressive behavior only after doses that greatly decreased the ability of mice to move. Even though akinesia seemed to account for inhibition of aggression there was no apparent correlation with binding to striatal D-2 receptors.

Language: en