Citation

Gurtovenko VM, Kuznetsova NI, Shumaĭlov IN, Proskuriakova TV, Eremina RV. Farmakol. Toksikol. 1989; 52(3): 83-86.

Vernacular Title

O vliianii karbidina na pokazateli okisleniia étanola pri éksperimental'noĭ alkogol'noĭ intoksikatsii.

Copyright

(Copyright © 1989, Izdatelstvo Meditsina)

DOI

unavailable

PMID

2571520

Abstract

The effect of carbidine on enzymes of ethanol and acetaldehyde oxidation, the rate of ethanol elimination and the parameters of ethanol consumption were studied during long-term alcoholic intoxication. Carbidine administration was shown to increase the activity of alcohol dehydrogenase of the liver tissue, to decrease the activity of aldehyde dehydrogenase with a low Km to acetaldehyde. Also, the rate of ethanol elimination and a relative amount of consumed ethanol increase at the expense of an increase of the volume of consumed liquid.

Language: ru