Citation

Machnik G, Bergert A, Justus J, Kunze P, Muller R, Reinhardt M, Schulz H, Stein G, Thiele R. Zentralbl. Allg. Pathol. 1988; 134(2): 167-177.

Vernacular Title

Arzneimittelhepatitis nach Dihydralazin mit tödlichem Verlauf.

Affiliation

Institut für Pathologische Anatomie, Friedrich-Schiller-Universität Jena.

Copyright

(Copyright © 1988, Gustav Fischer Verlag)

DOI

unavailable

PMID

3420978

Abstract

Adverse drug side effects of the antihypertensive substance dihydralazine have been increasingly observed in recent years. Damage is concentrated on the liver and is characterized by drug-induced hepatitis with confluent necrosis. Three cases (60 year old woman, 79 year old woman, 61 year old man) with lethal course after antihypertensive treatment, using dihydralazine are reported in this paper.

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