Citation

Rohrbaugh JW, Stapleton JM, Frowein HW, Adinoff B, Varner JL, Lane EA, Eckardt MJ, Linnoila M. Adv. Alcohol Subst. Abuse 1988; 7(3-4): 53-57.

Affiliation

Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892.

Copyright

(Copyright © 1988, Haworth Press)

DOI

10.1300/J251v07n03_09

PMID

3223435

Abstract

The acute effects of ethanol on skilled motor functions were examined in male social drinkers, under four doses ranging from 0 (placebo) to 1.05 g/kg lean body weight. The movement entailed a forewarned choice transitive motion of the arm and hand, aimed at a flanking target. Performance measures disclosed only small effects of ethanol on speed and accuracy of movement. The simultaneously-recorded movement-related brain potentials disclosed decreased involvement of frontal and posterior brain areas, suggesting that ethanol disrupted the planning and regulation of movement despite the overall preservation of reaction speed.

Language: en