Citation

Mewaldt SP, Ghoneim MM, Hinrichs JV. Psychopharmacology 1986; 88(2): 165-171.

Copyright

(Copyright © 1986, Holtzbrinck Springer Nature Publishing Group)

DOI

unavailable

PMID

3081928

Abstract

In a double-blind and randomized study, we assessed the comparative pharmacodynamic profiles and behavioral effects of diazepam and oxazepam administered to young healthy volunteers. Diazepam 0.3 mg/kg or oxazepam 1.2 mg/kg or placebo were each administered orally to 13 subjects who were tested with tasks which measured learning and memory, cognition, psychomotor performance and mood before and for 9 h after treatment. The two drugs had similar actions, although subjective effects were milder after oxazepam, which also had a slower onset of action. There was no evidence of rebound behavioral impairment.

Language: en