Citation

Bergschicker R, Just A. Biomed. Biochim. Acta 1986; 45(3): 401-412.

Vernacular Title

EEG-Untersuchungen an Ratten zur Bestimmung der Schwellendosis von Chlorpromazin unter Berücksichtigung des Vigilanzzustandes.

Copyright

(Copyright © 1986, Akademie Verlag)

DOI

unavailable

PMID

3707557

Abstract

Taking into account the actual vigilance status of the animals (awake, drowsiness, slow-wave-sleep) we were able to show EEG changes at lower chlorpromazine levels (0.42 mumole/kg b.w., i.p.) in contrast to 1.4 mumole/kg b.w., i.p.) in the model "without considering the vigilance status". These changes were especially pronounced during the awake state.

Language: de