Citation

Kong H, Ma Z, Wang S, Gong X, Zhang S, Zhang X. Anal. Chem. 2014; 86(15): 7734-7739.

Copyright

(Copyright © 2014, American Chemical Society)

DOI

10.1021/ac5016672

PMID

24985780

Abstract

With the inspiration of an ancient Chinese poison test approach, we report a rapid hydrogen sulfide detection strategy in specific areas of live cells using silver needles with good spatial resolution of 2×2 μm2. Besides the accurate-localization ability, this reflection-based strategy also has attractive merits of convenience and robust response when free pretreatment and short detection time is concerned. The success of endogenous H2S level evaluation in cellular cytoplasm and nuclear of human A549 cells promises the application potential of our strategy in scientific research and medical diagnosis.

Language: en