Citation

Meola JM. Clin. Chem. 1978; 24(9): 1642-1643.

Copyright

(Copyright © 1978, American Association for Clinical Chemistry)

DOI

unavailable

PMID

688632

Abstract

I describe a senstive colorimetric micromethod in which a pH 11.0 carbonate buffer is used to induce acetaminophen to react with Folin-Ciocalteau reagent at room temperature. These reagents and a simple solvent extraction favor formation of a stable indophenol dye with acetaminophen, giving this procedure a good degree of specificity.

RESULTS correlate well with those by liquid-chromatographic procedures, and day-to-day precision is less than 8%.

Language: en