Citation

Guerrero-Berroa E, Ravona-Springer R, Heymann A, Schmeidler J, Silverman JM, Sano M, Koifmann K, Preiss R, Hoffman H, Schnaider Beeri M. Dement. Geriatr. Cogn. Dis. Extra 2014; 4(1): 103-112.

Affiliation

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA ; The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat Gan, USA.

Copyright

(Copyright © 2014, Karger Publishers)

DOI

10.1159/000360280

PMID

24926308

PMCID

PMC4036126

Abstract

BACKGROUND/AIMS: Impaired motor function has been associated with cognitive impairment and dementia, but this relationship is poorly understood in elderly with type 2 diabetes (T2D). We thus investigated it in a large sample (n = 726) of cognitively normal elderly with T2D.

METHODS: In this cross-sectional study, hierarchical linear regressions assessed correlations of 3 motor measures (timed walk, grip strength, and self-reported motor difficulties) with episodic memory, attention/working memory, semantic categorization, executive function, and overall cognition controlling for demographics.

RESULTS: Longer timed walk and weaker grip strength were associated with poorer performance in all cognitive domains except episodic memory.

CONCLUSIONS: Associations of motor and cognitive functions in T2D and non-T2D samples are consistent. A lack of association of motor function with episodic memory may suggest non-Alzheimer's disease-related underlying mechanisms.

Language: en