Citation

Gelbke HP, Lesch P, Spiegelhalder B, Schmidt G. Blutalkohol 1978; 15(1): 11-17.

Copyright

(Copyright © 1978, International Committee on Alcohol, Drugs and Traffic Safety and Bund gegen Alkohol und Drogen im Straßenverkehr, Publisher Steintor Verlag)

DOI

unavailable

PMID

unavailable

Abstract

Simultaneous determinations of alcohol concentration in blood (BAC) and cerebro-spinal fluid (CAC) were carried out on samples from 509 bodies containing alcohol in one or both of these fluids. The least square regression analysis gave a coefficient of correlation, r = 0.943, and the equation for the regression line: CAC = 1.35 X BAC-0.11. 0.11. From this conversion factor FC-B of 0.74 is derived for the calculation of the BAC from the CAC. This value lies within the theoretically determined range of 0.737-0.767 for post-mortem material. Similar values for the FC-B and the coefficient of correlation were obtained from the statistical evaluation of the data of other authors. From these results it may be inferred that the diffusion equilibrium between blood and cerebro-spinal fluid occurs rapidly. The magnitude of the conversion factor FC-B and its range expressed as standard deviation were independant of the height of the blood alcohol concentration over a wide range.