Citation

Gelbke HP, Lesch P, Schmidt G. Blutalkohol 1978; 15(2): 115-124.

Copyright

(Copyright © 1978, International Committee on Alcohol, Drugs and Traffic Safety and Bund gegen Alkohol und Drogen im Straßenverkehr, Publisher Steintor Verlag)

DOI

unavailable

PMID

unavailable

Abstract

Simultaneous determinations of alcohol concentrations in blood (BAC), vitreous humor (VAC) and cerebro-spinal fluid (CAC) were carried out on samples from 440 bodies having alcohol in these body fluids. The least square regression analysis for VAC and CAC gave a coefficient of correlation, r=0.954, and the equation for the regression line: VAC=0.90 x CAC - 0.04. From this a conversion factor F(C-V) of 0.90 is derived for the calculation of the VAC from CAC. This value lies clearly below the theoretical expected value of F(C-V)=0.99. It may hence be inferred that diffusion equilibrium of alcohol between blood and cerebro-spinal fluid occurs rapidly and in comparison more slowly between blood and vitreous humor. Similar results were obtained with the analysis of cases in which the VAC and/or the CAC was lower than the BAC.