Citation

Ghosh S. Indian J. Crit. Care Med. 2014; 18(4): 244-246.

Affiliation

Department of Critical Care Medicine, Fortis-Escorts Hospital, NIT, Faridabad, Haryana, India.

Copyright

(Copyright © 2014, Indian Society of Critical Care Medicine, Publisher Medknow Publications)

DOI

10.4103/0972-5229.130578

PMID

24872656

Abstract

Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate (Trade Names: DDVP, Vapona, etc.) is a highly volatile organophosphate, widely used as an organophosphorus insecticide.

Current case report describes a 37-year-old female patient who was admitted to the hospital following subcutaneous injection of Dichlorvos with an insulin syringe. The only peripheral cholinergic sign observed on admission was excessive salivation with bilateral pyramidal tract signs. Locally she had necrosis of skin and subcutaneous tissue with surrounding blisters. In the subsequent course of her illness, she developed respiratory arrest requiring ventilator support. She also had delayed extrapyramidal manifestations. Relevant literature is reviewed. Possibility of route-specific, delayed predominant central nervous system effect of Dichlorvos postulated.

Language: en