Citation

Fischer G, Kampmann H. Blutalkohol 1982; 19(1): 53-74.

Copyright

(Copyright © 1982, International Committee on Alcohol, Drugs and Traffic Safety and Bund gegen Alkohol und Drogen im Straßenverkehr, Publisher Steintor Verlag)

DOI

unavailable

PMID

unavailable

Abstract

The purpose of the investigation was to find the distribution of acetaldehyde (AcH) in human blood. Acetaldehyde formed from ethanol can be found almost exclusively on red cells; in plasma only small concentrations of acetaldehyde can be shown. It is presumed that the acetaldehyde formed in vivo is not present in blood in a free form. Thus, the 'circulating' acetaldehyde has no extravascular effect and should be excluded as the cause of alcoholic organic lesions. In human plasma, a reduction of the acetaldehyde concentrations was established which - in contrast to the AcH metabolism of erythrocytes - is not due to enzymes (in vitro).