Citation

Neulieb R. Pharmacol. Biochem. Behav. 1984; 21(Suppl 1): 15-16.

Copyright

(Copyright © 1984, Elsevier Publishing)

DOI

unavailable

PMID

6522428

Abstract

The author volunteered to experience on himself the effect of short-term, i.e., 36 consecutive days, oral administration of cesium chloride. Cesium chloride was given 6 g per day into two equally divided doses. The drug was dissolved in 8 ounces fluid and consumed immediately after the morning and evening meals which were diet-restricted to wheat bran and certain grain products, to attain approximately 1% potassium intake, for the initial 3 weeks. Bread products were discontinued and yogurt and cottage cheese products were reinstituted for the two week period that followed prior to reinstituting of the preceding food regimens. There was an initial general feeling of well-being and heightened sense perception. A gradual decrease in appetite was noted initially before it was stabilized at a later date. Discontinuation of rich bread meals resulted in pre-nausea sensation which was followed by diarrhea 48 hr later. The institution of high potassium nutrition decreased the feeling of nausea and abolished diarrhea. A "tingling" sensation in the lip and cheek regions was experienced 15 min subsequent the cesium chloride dosage compared to same sensation occurring at moderate intensity in hands and feet at end of the experiment. No adverse effects of CsCl were noted in performance of mathematical analyses or in driving skill. It is concluded that CsCl is devoid from toxicity provided adequate diet and supplements are administered.

Language: en