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Citation |
Agius R, Nadulski T, Moore C. Forensic Sci. Int. 2012; 215(1-3): 38-45. |
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Affiliation |
Labor Krone, Siemensstr. 40, 32105 Bad Salzuflen, Germany. ragius@laborkrone.de |
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Copyright |
(Copyright © 2012, Elsevier Publishing) |
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DOI |
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PMID |
22075096 |
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Abstract |
LUCIO-Direct-enzyme linked immunosorbent assay (ELISA) tests were validated for the screening of drugs of abuse cannabis, opiates, amphetamines and cocaine in urine for the new German medical and psychological assessment (MPA) guidelines with subsequent gas chromatographic-mass spectrometric (GC-MS) confirmation. The screening cut-offs corresponding to 10 ng/mL 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid (THC-COOH), 50 ng/mL amphetamine, 25 ng/mL morphine and codeine and 30 ng/mL benzoylecgonine were chosen at the point where the number of false negatives was lower than 1%. Due to their accuracy, ease of use and rapid analysis, these ELISA tests are very promising for cases where a large proportion of the tests are expected to be negative such as for abstinence monitoring as part of the driving licence re-granting process. Language: en |