Citation

Camicioli R. Neurology 2013; 81(5): 441.

Copyright

(Copyright © 2013, Lippincott Williams and Wilkins)

DOI

10.1212/WNL.0b013e31829d87aa

PMID

23803319

Abstract

Dementia and falls are major public health problems. The current study links them by showing that "silent" CNS amyloid (PET evidence for amyloid/CSF decrease in amyloid) and CSF tau species increase the risk of falls. Falls, therefore, may be a more sensitive clue to a "system failure" than conventional clinical measures.(1) Since falls are complex accidents that have multiple contributing factors, the mechanisms by which amyloid deposition increases their risk remain unclear. Strengths of the study include its prospective design with monthly falls assessment for 1 year.

Language: en