Citation

Mrzljak A, Kosuta I, Skrtic A, Kanizaj TF, Vrhovac R. Case Rep. Gastroenterol. 2013; 7(1): 19-24.

Affiliation

Department of Medicine, University Hospital Merkur, Zagreb, Croatia ; Department of School of Medicine, University of Zagreb, Zagreb, Croatia.

Copyright

(Copyright © 2013, Karger Publishers)

DOI

10.1159/000343651

PMID

23467452

Abstract

Noni juice is a popular herbal dietary supplement globally used for preventive or therapeutic purposes in a variety of ailments, claiming to exhibit hepatoprotective properties as well. Herein we present the case of a 38-year-old woman who developed acute liver injury associated with noni juice consumption on a long-term (9 months) anticonvulsant therapy. Clinical presentation and liver biopsy were consistent with severe, predominantly hepatocellular type of injury. Both agents were stopped and corticosteroids were initiated. Five months later the patient had fully recovered. Although in the literature the hepatotoxicity of noni juice remains speculative, sporadic but emerging cases of noni juice-associated liver injury address the need to clarify and investigate potential harmful effects associated with this supplement.

Language: en