Citation

Sommerfeld K, Łukasik-Głebocka M, Zielińska-Psuja B. Przegl. Lek. 2012; 69(8): 435-438.

Vernacular Title

Znaczenie diagnostyczne oznaczenia glikolu etylenowego w ostrych zatruciach--analiza przypadków z terenu województwa wielkopolskiego.

Affiliation

Katedra i Zakład Toksykologii, Uniwersytet Medyczny im. K. Marcinkowskiego w Poznaniu.

Copyright

(Copyright © 2012, Przeglad Lekarski)

DOI

unavailable

PMID

23243902

Abstract

Ethylene glycol (EG) is a multidirectional, dihydric alcohol, which is widely used in food, chemical and automotive industries. EG is a compound of similar toxicity to ethanol (EA). The EG biotransformation undergoes, mainly to glycolaldehyde and acids: glycolic, glyoxylic and oxalic acid, such metabolites, which exhibit strong narcotic effect on the central nervous system, causing profound metabolic acidosis and lead to severe nephropathy. Due to the wide availability of products containing ethylene glycol and its potential toxicity, in the case of the alcohol poisoning, the significant role in the diagnosis play: medical interview, observation of characteristic clinical symptoms, basic laboratory tests and detection of ethylene glycol in the biological material that confirm EG poisoning.

Language: pl