Citation

Thanacoody R. Medicine (Abingdon) 2007; 35(11): 619.

Copyright

(Copyright © 2007, Medicine Publishing)

DOI

10.1016/j.mpmed.2007.08.008

PMID

unavailable

Abstract

Gamma-hydroxybutyric acid (GHB; liquid ecstasy, sodium oxybate) is a drug of abuse which is increasingly used recreationally and has been implicated in cases of 'drug rape'. GHB-intoxicated patients may appear sedated or may show paradoxical agitation. After ingestion of a toxic amount of GHB, rapid onset of respiratory depression and deep coma may occur, resolving spontaneously within 24 hours with supportive care. In regular users, a withdrawal syndrome similar to alcohol withdrawal is also recognized.