Citation

Szpak D, Groszek B, Piotrowski W, Scisłowski M. Przegl. Lek. 2003; 60(4): 257-261.

Vernacular Title

Ciezkie zatrucie mieszane diltiazemem, potasem i magnezem--opis przypadku.

Affiliation

Klinika Toksykologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie, 31-826 Kraków, Os. Złotej Jesieni 1.

Copyright

(Copyright © 2003, Przeglad Lekarski)

DOI

unavailable

PMID

14569897

Abstract

We report the case of 52-year-old woman, who ingested 3.6 g of diltiazem, 16 g of potassium chloride and 6.5 g of magnesium, in a suicide attempt 4 hours before admission. She developed cardiorespiratory failure, with severe hypotonia and acute renal failure, in ECG third degree atrioventricular block was stated. The highest potassium concentration was 8.0 mmol/l, magnesium 2.15 mmol/l. As a result of multiple pharmacologic intervention, including intravenous fluids, calcium, glucagon, dopamine, dobutamine, norepinephrine, transvenous pacing and peritoneal dialysis (haemodynamic instability makes haemodialysis noneffective) the haemodynamic stabilization of cardiovascular system and normalization of potassium and magnesium concentration were achieved. The diltiazem concentration was measured using liquid chromatography, the result was 0.89 microgram/ml. She was discharged in a good clinical condition on day 26th.

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