Citation

Makar'iants ML. Klin. Med. (Mosk) 2003; 81(4): 58-60.

Vernacular Title

Aktual'nye voprosy bezopasnosti paratsetamola kak predstavitelia bezretsepturnykh

Copyright

(Copyright © 2003, Ministerstvo Zdravoochranenija SSSR)

DOI

unavailable

PMID

12785227

Abstract

Paracetamol is a well-known analgetic-antipiretic drug widely used in medical practice. In therapeutic doses (4 g/day for adults and 60 mg/kg/day for children) paracetamol relieves fever and non-severe pain with minimal risk of complications both in adults and children. But medical professionals should know that in extremely high doses (above 10 g for adults) paracetamol has a hepatotoxic effect. Overdose intake of paracetamol in Russia happens rarely, it occurs by chance or in attempted suicide. In such a case the antidote must be used to protect the liver. This antidote for paracetamol is N-acetylcysteine.

Language: ru