Citation

Wolfram G, Drummer C, Helbig R, Hesse C, Klan R, Sittner WD, Baisch F. Eur. J. Med. Res. 1999; 4(9): 379-381.

Affiliation

Institut für Flugmedizin der RWTH Aachen, Pauwelsstr. 30, 52057 Aachen, Germany. wolfram@pbmail.me.kp.dlr.de

Copyright

(Copyright © 1999, Holtzbrinck Springer Nature Publishing Group)

DOI

unavailable

PMID

10477504

Abstract

A model to investigate the functional capacity (psychomental performance) under stressful conditions was developed. Twenty eight patients with mild hypertension receiving Nitrendipine (20 mg) for 30 days were tested under hypoxic (16% oxygen) and/or orthostatic (-30 mmHg lower body negative pressure) conditions using a subset of the AGARD battery. The main effect was a decreasing performance of the grammatical reasoning task (GRT) under hypoxia or the combination of hypoxia and orthostasis. A simultaneous application of stressors while performing psychometric test batteries may be useful to reveal pharmaceutical influences on human performance and may help to recommend the use of drugs in occupational medicine.

Language: en