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Journal Article

Citation

Dehon B, Chagnon JL, Vinner E, Pommery J, Mathieu D, Lhermitte M. Biomed. Chromatogr. 1999; 13(3): 235-238.

Affiliation

Laboratoire de Biochimie et Biologie Moléculaire, Hôpital Calmette, Lille, France.

Copyright

(Copyright © 1999, John Wiley and Sons)

DOI

10.1002/(SICI)1099-0801(199905)13:3<235::AID-BMC827>3.0.CO;2-N

PMID

10375125

Abstract

A case involving a suicide by the ingestion of colchicine tablets is presented. Liquid chromatography has been used to measure the drug level in blood and in post-mortem tissues of the patient (a 42-year-old man). Plasma concentration 24 h after ingestion was 4.5 ng/mL. On autopsy, the kidney showed the highest concentration (396 ng/g). High concentrations were also found in the liver (347 ng/g) and heart (334 ng/g). Low concentrations were detected in the lung (58 ng/g), muscle (10 ng/g) and brain (5 ng/g).


Language: en

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