Citation

Tanoue K, Matsui K, Nozawa K, Aida N. Acta Paediatr. 2012; 101(6): 614-617.

Affiliation

Department of general medicine, Kanagawa children's medical center Department of radiology, Kanagawa children's medical center.

Copyright

(Copyright © 2012, John Wiley and Sons)

DOI

10.1111/j.1651-2227.2012.02635.x

PMID

22353249

Abstract

Aim:  The aim of this study was to evaluate the value of early radiological investigations in predicting the long-term neurodevelopmental outcome of patients with inflicted traumatic brain injury (ITBI). Methods:  In 28 patients with ITBI, radiological investigations were performed during the acute phase of injury (0-3 days) and during the early postinjury phase (4 days to 1 month). The clinical outcome in survivors (n=24) was based on the Glasgow Outcome Score. Results:  Four of 28 infants died and five were severely disabled. Six infants had moderate disability. Detection of changes in the basal ganglia (p < 0.000005) or brain stem (p < 0.01), diffuse edema (p < 0.005), transtentorial herniation (p < 0.01), subarachnoid hemorrhage (p < 0.05) or parenchymal injury (p < 0.05) by neuroimaging during the first three days, and detection of changes in the basal ganglia (p < 0.0005) or brain stem (p < 0.05) or parenchymal injury (p < 0.01) during one month were significantly associated with poor long-term outcome. Conclusion:  Radiologic findings during the first month were significantly associated with the long-term outcome. Especially, basal ganglia lesions were associated with a poor outcome. © 2012 The Author(s)/Acta Pædiatrica © 2012 Foundation Acta Pædiatrica.

Language: en