Citation

Tan M, Tan U. Int. J. Neurosci. 2001; 106(1-2): 87-94.

Affiliation

Department of Neurology, Medical Faculty, Karadeniz Technical University, Trabzon, Turkey.

Copyright

(Copyright © 2001, Informa - Taylor and Francis Group)

DOI

unavailable

PMID

11264910

Abstract

The effects of testosterone and clomiphene on epilepsy was studied in a young man with posttraumatic seizures. In the control period, digital EEG and visual evoked potentials (VEPs) were recorded under carbamazapine therapy. After testosterone (T), seizures lessened and almost disappeared; the theta, delta, alpha, and beta powers decreased; VEPs increased. After clomiphene, VEPs considerably increased in size; clinical picture slightly improved; EEG power spectrum remained unchanged. It was suggested that T may be beneficial for epilepsy treatment by suppressing the EEG synchronization (slow wave activity) and attenuating the entropy state of the epileptic brain.

Language: en