Citation

Kiyota K, Hamabe Y. Chudoku Kenkyu 2001; 14(1): 57-60.

Affiliation

Tertiary Emergency Medical Center, Tokyo Metropolitan Bokutoh Hospital.

Copyright

(Copyright © 2001, Yakugyo Jihosha)

DOI

unavailable

PMID

11381464

Abstract

A-19-year-old girl ingested 7.4 g of Isoniazid (INH) and 14.5 g of Ethambutol (EB) intentionally. She presented repetitive generalized convulsions with metabolic acidosis, treated with diazepam and 7.5 g of Pyridoxine (Vitamin B6). During day 4 and 5, liver dysfunction worsened and prothrombin time declined below 5%. She was treated with infusion of fresh frozen plasma and fully recovered on day 13. Serum concentration of INH and EB at 5 hours after ingestion was 7.6, 0.94 micrograms/ml respectively.

Language: ja