Citation

Buskila D, Mader R. Best Pract. Res. Clin. Rheumatol. 2011; 25(2): 199-207.

Affiliation

Department of Medicine H, Soroka Medical Center and Faculty of Health Sciences, Ben Gurion University, P.O. Box 151, 84101 Beer Sheva, Israel.

Copyright

(Copyright © 2011, Elsevier Publishing)

DOI

10.1016/j.berh.2011.01.003

PMID

22094196

Abstract

In the past decade, major progress has been made in our understanding of fibromyalgia syndrome (FMS). Various triggers have been implicated as contributing to symptom development in FMS when genetically susceptible individuals are challenged. A substantial amount of data points towards the association between trauma and chronic widespread pain/fibromyalgia syndrome (CWP/FMS). There is abundant data suggesting that the pathogenesis of CWP/FMS might be related to cervical spine injury. Furthermore, several persistent local pain conditions may progress to CWP/FMS. These conditions may share a common pathogenic mechanism namely, central sensitisation. Physical trauma and emotional trauma co-exist in many traumatic events and may interact in the pathogenesis of CWP/FMS.

Language: en