Citation

Ferlan I, Ferlan A, King T, Russell FE. Toxicon 1983; 21(4): 570-574.

Copyright

(Copyright © 1983, Elsevier Publishing)

DOI

unavailable

PMID

6623495

Abstract

Following the bite by Rhabdophis subminatus, preliminary studies were instituted on its venom to determine the mechanism of the clinical poisoning. A method for milking these snakes is presented. The i.v. LD50 in mice was 1.29 mg/kg. Three peaks were obtained on Sephadex G-100 and although none were lethal by themselves, a combination of two of the peaks produced immediate death in mice. The venom had no phosphodiesterase, fibrinolytic or thrombin-like activities, but it did have some phospholipase activity. Further biochemical and pharmacological studies are in progress.

Language: en