Citation

Linnoila M, Johnson J, Dubyoski T, Ross R, Buchsbaum M, Potter WZ, Weingartner H. Acta Psychiatr. Scand. Suppl. 1983; 308: 175-181.

Copyright

(Copyright © 1983, John Wiley and Sons)

DOI

unavailable

PMID

6230891

Abstract

Interactions of three antidepressants--amitriptyline, desipramine and zimeldine--with a single 0.8 g/kg body weight dose of alcohol were studied in healthy male volunteers. The dependent variables were performance measurements in the Continuous Performance Task and a cognitive memory task. Alcohol and desipramine showed different and specific deleterious effects on cognitive and memory functions, whereas amitriptyline produced a more generalized impairment. Zimeldine slightly improved performance in the Continuous Performance Task and antagonized effects of alcohol in both tasks.

Language: en