Citation

Shimanko II, Nazarenko AA, Osmanov SK, Tsepliaeva GI, Kuz'mina NS, Lebedeva IuN, Zimina LN. Vestn. Akad. Med. Nauk SSSR 1990; (3): 37-39.

Vernacular Title

Otsenka klinicheskoi znachimosti opredeleniia urovnia plazmennogo fibronektina

Copyright

(Copyright © 1990, Izd-vo Akademii Medit͡sinskikh Nauk SSSR)

DOI

unavailable

PMID

2353535

Abstract

Changes in plasma fibronectin (FN) levels in acute toxic conditions have been studied in 24 patients. A significant reduction of FN concentration was found within the first days of the disease; further changes in the FN levels are related to the disease outcome and have a prognostic value. An inverse correlation was found between the FN concentration and other blood biochemical parameters (LDH, creatinine, and urea). Developed renal insufficiency in the presence of hypofibronectinemia suggests a poor prognosis of the disease.

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