Citation

Lewis DH, Bengtsson MB, Larsson J, Liljedahl SO. Acta Chir. Scand. Suppl. 1979; 489: 225-230.

Copyright

(Copyright © 1979, P A Norstedt Soner)

DOI

unavailable

PMID

291259

Abstract

Anesthetized pigs were wounded in the thigh with a spherical missile at an impact velocity of 1500 m/sec. Arterial blood samples were taken before injury and at frequent intervals up to 12 hours after injury. Unbound (free) and total kallikrein (kallikrein + prekallikrein) were analyzed with a chromogenic substrate (S-2302, Kabi, Sweden) in which enzyme activity is determined spectrophotometrically by the development of a yellow colour. The results indicate an activation of the kallikrein-kinin system in bullet wounding, the significance of which remains to be determined.

Language: en