Citation

Auer L, Petek W. Acta Neurochir. (Wien) 1976; 33(3-4): 301-309.

Vernacular Title

Serumproteinveranderungen bei Patienten mit Schadel-Hirn-Trauma - Vergleich

Copyright

(Copyright © 1976, Holtzbrinck Springer Nature Publishing Group)

DOI

unavailable

PMID

60046

Abstract

Quantitive estimations of serum proteins, including Alpha 2M globulin, from 34 patients suffering from craniocerbral trauma have been carried out. The mean value curves over a period of two weeks following trauma are presented graphically. After severe injuries, depending on the size of the cerebral lesions, an increase in Alpha 2 of prognostic significance has been observed. Levels of Alpha 2M do not correlate directly with Alpha 2 globulin, and tend to fall initially. Falls in the first three days after injury may be prognostically significant from the point of view of the prediction of a lethal outcome. There are no significant changes in the levels of total protein, albumin, Beta globulin or Gamma globulin, but Alpha 1 globulin follows the curve of Alpha 2, although to a less marked degree. Correlations between serum protease activites and increases in Alpha 2 due to enzymatically active complexes are unconnected with Alpha 2M, a decrease in which indicates increased inhibitor activity and exhaustion of the inhibitor system.

Language: de