Citation

Knott VJ, Lapierre YD. Prog. Neuropsychopharmacol. Biol. Psychiatry 1991; 15(2): 249-255.

Affiliation

Royal Ottawa Hospital, Ontario, Canada.

Copyright

(Copyright © 1991, Elsevier Publishing)

DOI

unavailable

PMID

1871325

Abstract

1. Depressive psychomotor retardation, as observed by delayed reaction times (RT), may be related to a slowing in information processing speed. 2. Two separate studies compared indices of information processing speed in depressed patients and non-clinical controls by segmenting behavioral RT with brain event-related potentials (ERPs) and electromyographic (EMG) responses. 3. In Study I, slower behavioral RTs in depression were concomitant with slower central processing times (CPT) but not motor execution times (MET). 4. In Study II, P165, a putative early cognitive ERP related to 'stimulus evaluation time', was found to be slower but within normal range in depressed patients.

Language: en