Citation

Nestor PG, Parasuraman R, Haxby JV, Grady CL. Neuropsychologia 1991; 29(5): 379-387.

Affiliation

Department of Psychology, Catholic University of America.

Copyright

(Copyright © 1991, Elsevier Publishing)

DOI

unavailable

PMID

1886681

Abstract

The relationship between reaction time (RT) measures under single-task and dual-task conditions and resting levels of brain metabolism, as measured by positron emission tomography (PET), was examined in patients with mild dementia of the Alzheimer type (DAT) and age- and educationally-matched controls. Slowing of RT in dual-task but not single-task conditions correlated with reductions in brain metabolism in right premotor and right parietal association areas only for the mild DAT patients. The results suggest a relation between divided attention deficits and metabolic dysfunction of right frontal and parietal lobes in mild DAT patients.

Language: en