Citation

Ruppelt BM, Pereira EF, Gonçalves LC, Pereira NA. Mem. Inst. Oswaldo Cruz 1991; 86(Suppl 2): 203-205.

Affiliation

Departamento de Farmacologia, CCS-ICB, UFRJ, Ilha do Fundão, Rio de Janeiro, Brasil.

Copyright

(Copyright © 1991, Instituto Oswaldo Cruz)

DOI

unavailable

PMID

1842002

Abstract

We have observed that several plants used popularly as anti-snake venom show anti-inflammatory activity. From the list prepared by Rizzini, Mors and Pereira some species have been selected and tested for analgesic activity (number of contortions) and anti-inflammatory activity (Evans blue dye diffusion--1% solution) according to Whittle's technique (intraperitoneal administration of 0.1 N-acetic acid 0.1 ml/10 g) in mice. Previous oral administration of a 10% infusion (dry plant) or 20% (fresh plant) corresponding to 1 or 2 g/kg of Apuleia leiocarpa, Casearia sylvestris, Brunfelsia uniflora, Chiococca brachiata, Cynara scolymus, Dorstenia brasiliensis, Elephantopus scaber, Marsypianthes chamaedrys, Mikania glomerata and Trianosperma tayuya demonstrated analgesic and/or anti-inflammatory activities of varied intensity.

Language: en