Citation

Henderson RA, Lane S, Henry JA. Hum. Exp. Toxicol. 1991; 10(1): 59-62.

Affiliation

Guy's Hospital, London, UK.

Copyright

(Copyright © 1991, SAGE Publishing)

DOI

unavailable

PMID

1673626

Abstract

A 48-year-old woman developed QT prolongation and episodes of life-threatening ventricular tachycardia (torsades de pointes) after intentional overdose of haloperidol and orphenadrine. The arrhythmia did not respond to conventional anti-arrhythmic therapy but was suppressed by atrial overdrive pacing. A literature review identified haloperidol as the most likely cause of the torsades de pointes.

Language: en