Citation

LoDico CP, Levine BS, Goldberger BA, Caplan YH. J. Anal. Toxicol. 1992; 16(1): 57-59.

Affiliation

Office of the Chief Medical Examiner, Toxicology Laboratory, Baltimore, Maryland 21201.

Copyright

(Copyright © 1992, Preston Publications)

DOI

unavailable

PMID

1640700

Abstract

A fatality due to the ingestion of isoniazid, a tuberculostatic agent, is presented. Isoniazid was extracted by a single step extraction procedure, derivatized with trifluoroacetic anhydride, and identified and quantified by gas chromatography/mass spectrometry (GC/MS). The distribution of isoniazid was as follows: heart blood 43 mg/L, subclavian blood 94 mg/L, urine 470 mg/L, bile 900 mg/L, liver 650 mg/Kg, kidney 110 mg/Kg, and stomach contents 4 mg.

Language: en