Citation

Collee GG, Samra GS, Hanson GC. Intensive Care Med. 1992; 18(3): 170-171.

Affiliation

Intensive Care Unit, Whipp's Cross Hospital, Leytonstone, London, UK.

Copyright

(Copyright © 1992, Holtzbrinck Springer Nature Publishing Group)

DOI

unavailable

PMID

1644965

Abstract

A 13-year-old boy was admitted to hospital 45 min after the ingestion of approximately 750 mg of chloroquine base. A few minutes after gastric lavage with warm water he developed ventricular fibrillation from which he was promptly resuscitated. The plasma concentration of chloroquine was 4.2 mumol/l; significantly lower than the concentrations previously associated with a fatal outcome in adults. The clinical and electrocardiographic effects of chloroquine poisoning are discussed, and the literature reviewed regarding the role of specific management with diazepam and adrenaline infusions. A period of twenty four hours electrocardiographic (ECG) monitoring and pulse oximetry in an intensive care unit is advocated for all patient with ECG changes following chloroquine overdose.

Language: en