Citation

Goldberg JF, Garno JL, Leon AC, Kocsis JH, Portera L. Am. J. Psychiatry 1998; 155(12): 1753-1755.

Affiliation

Bipolar Disorders Research Clinic, New York Hospital, NY 10021, USA.

Copyright

(Copyright © 1998, American Psychiatric Association)

DOI

unavailable

PMID

9842787

Abstract

OBJECTIVE: The authors' goal was to examine suicidality in relation to acute symptom remission in inpatients with mixed and pure bipolar disorder. METHOD: Using chart review of 184 adult inpatients with bipolar I disorder, the authors assessed patients' past and current suicidality, other psychopathology, treatment, and remission. RESULTS: Past, current, and recurrent suicidality were significantly more common among patients with mixed mania than among those with pure mania. The probability of remission declined by 49% for every suicide attempt made before the index manic episode. Mixed mania, multiple previous hospitalizations, and previous suicide attempts were significantly associated with current suicidality. CONCLUSIONS: Suicidality is linked with mixed manic states and may be a clinical marker for recurrent dysphoric mania. Multiple suicide attempts are associated with nonremission from mixed manic episodes.

Language: en