Citation

Behrendt S, Kaatsch HJ, Schwinger R. Ophthalmologe 1996; 93(4): 367-370.

Vernacular Title

Visuell evozierte Potentiale bei niedrigen Blutalkoholkonzentrationen.

Affiliation

Klinik für Ophthalmologie, Christian-Albrechts-Universität, Kiel.

Copyright

(Copyright © 1996, Holtzbrinck Springer Nature Publishing Group)

DOI

unavailable

PMID

8963132

Abstract

BACKGROUND: Both the acute toxic effects of ethanol on the central nervous system and the effects of chronic alcohol consumption on the optic nerve (tobacco-alcohol amblyopia) are well known. We investigated the acute effect of low blood alcohol concentrations on visual evoked potentials. MATERIALS AND METHODS: A pattern VEP (stimulation by TV monitor, alternating chequerboard patterns, 45', 2 Hz, contrast 90%) was performed in ten healthy volunteers in sober condition and 0, 30, 60, 90 and 120 min following ingestion of 1 g/kg body weight ethanol (resulting in a blood alcohol concentration of 0.8-1.1%). Blood samples were drawn from the cubital vein simultaneously with each recording to determine blood alcohol concentration. RESULTS: Neither peak latencies nor amplitudes showed significant changes related to blood alcohol concentration. CONCLUSION: No acute impairment of the optic nerve caused by ingestion of low doses of alcohol could be found using pattern VEP.

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