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Journal Article

Citation

Cox RD, Orledge J. Clin. Toxicol. (Phila) 2011; 49(3): 167-170.

Affiliation

Mississippi Poison Control Center, Department of Emergency Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA.

Copyright

(Copyright © 2011, Informa - Taylor and Francis Group)

DOI

10.3109/15563650.2011.559473

PMID

21495885

Abstract

Introduction. Monosodium methanearsonate (MSMA) is an organo-arsenic containing herbicide. There is scant information available concerning the toxicity of this chemical in humans. Case Report. Seven male teenagers, 15-18 years of age, inadvertently used a MSMA herbicide as cooking oil to fry fish. All had early gastrointestinal (GI) symptoms. Whole blood arsenic concentrations ranged from 348 to 613 μg/L and initial urine levels ranged from 81 400 to 226 300 μg-arsenic/g-creatinine. They were all treated with dimercaprol for 1 day and succimer for 19 days. They were followed for 15-months and had no evidence of any serious toxicity. Conclusion. MSMA produces early GI symptoms and very high levels of arsenic in blood and urine, but no evidence of long-term toxicity.


Language: en

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