Citation

Hamazaki T, Hamazaki K. Prog. Lipid Res. 2008; 47(4): 221-232.

Affiliation

Department of Clinical Sciences, Institute of Natural Medicine, University of Toyama, 2680 Sugitani, Toyama-city, Toyama 9300194, Japan. hamazaki@inm.u-toyama.ac.jp

Copyright

(Copyright © 2008, Pergamon Press)

DOI

10.1016/j.plipres.2008.02.001

PMID

18358242

Abstract

Fish oils have long been known to protect the heart from ischemic heart disease and fatal arrhythmia. Recently they have also been suggested to protect the heart in a literal sense! Although not all reports on fish oils and psychiatric disorder support the latter notion, many of them claim that fish oils were effective. The point is that, different from currently prescribed psychiatric medicines, fish oils do not do harm to any part of the body. We have been working on the effects of fish oils on aggressive behavior and hostility. Unfortunately this area of research is not mature yet. The number of related papers is rather limited, so we will take aggression and/or hostility in a broader sense including oppositional behavior, violence etc. in this review. We found fourteen intervention studies checking the effects of fish oils on aggressive behavior. Eleven of them showed the aggression/hostility-controlling effects of fish oils one way or another. We did not try to summarize those effects by meta-analysis, because we thought that the methods of research were too heterogeneous. The mechanisms as to how fish oils affect aggression/hostility is not clear yet, but several possible mechanisms have been postulated. Among them, activation of the serotonergic neuron system is the most promising. The research area of fish oils and aggression/hostility is clearly important from the medical and social points of view.

Language: en