Citation

Sladowska H, Bartoszko-Malik A, Zawisza T. Farmaco 1990; 45(1): 101-110.

Affiliation

Department of Chemistry of Drugs, School of Medicine, Wroclaw, Tamka, Poland.

Copyright

(Copyright © 1990, Elsevier Publishing)

DOI

unavailable

PMID

2337441

Abstract

Condensation of diethyl 2-amino-6-methylpyridine-3,4-dicarboxylate with phenyl or cyclohexyl isocyanates gave the corresponding derivatives of ethyl 7-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrido [2,3-d]pyrimidine- 5-carboxylate[(V), (VI)]. Alkylation of (V) and (VI) afforded the corresponding N-1 substituted derivatives (XI-XIX).

Language: en