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Journal Article

Citation

Nelson EC, Lynskey MT, Heath AC, Madden PAF, Martin NG. Twin Res. Hum. Genet. 2010; 13(2): 121-130.

Affiliation

Department of Psychiatry, Washington University School of Medicine, Midwest Alcoholism Research Center, St. Louis, MO 63110, United States of America. nelsone@wustl.edu

Copyright

(Copyright © 2010, Australian Academic Press)

DOI

10.1375/twin.13.2.121

PMID

20397742

PMCID

PMC2995987

Abstract

Childhood sexual abuse (CSA) and physical abuse (CPA) are well-established risk-factors for a wide of range of proximal and distal outcomes. The lack of availability of an optimal design for examining abuse and its consequences has resulted in the use of various approaches, each having its own limitations. We describe the Childhood Trauma Study, which ascertained families from a large young adult Australian twin cohort on the basis of twins' responses to screening questions assessing CSA and CPA. We report data from 3407 participants including twins, non-twin siblings, and their parents. Our data demonstrate the feasibility of using a comprehensive assessment to evaluate retrospective history of childhood abuse in an adult sample. We observed that risk for each form of abuse increased incrementally with the number of parents with alcohol problems. Psychometric properties of our measures of CSA and CPA including reasonable long-term stability, construct validity, and evidence of familial corroboration compare favorably with those of other reports in which samples were considerably younger and assessments were repeated over shorter intervals.


Language: en

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