Citation

Buckley PF, Ibrahim ZY, Singer B, Orr B, Donenwirth K, Brar PS. J. Am. Acad. Psychiatry Law 1997; 25(2): 173-181.

Affiliation

Northcoast Behavioral Healthcare System, Cleveland, OH 44067, USA.

Copyright

(Copyright © 1997, American Academy of Psychiatry and the Law, Publisher American Academy of Psychiatry and the Law)

DOI

unavailable

PMID

9213289

Abstract

The advent of novel antipsychotic medications has raised treatment expectations for patients with severe mental illness. In this regard, clozapine has been particularly effective in reducing aggressive behavior in patients with schizophrenia. This study compared the efficacy of risperidone and conventional antipsychotic medications in the management of hostile patients. Improvements in the level of aggression were evident over time in both treatment groups, and a similar response between risperidone and typical antipsychotics was observed. Future studies should address the relative role of typical antipsychotics, adjunctive agents, and novel antipsychotic medications in the pharmacological management of persistent aggression in patients with schizophrenia.

Language: en