Citation

Mursch K, Trnovec S, Ratz H, Hammer D, Horré R, Klinghammer A, de Hoog S, Behnke-Mursch J. Childs Nerv. Syst. 2006; 22(2): 189-192.

Affiliation

Department of Neurosurgery, Zentralklinik, Robert-Koch Allee 9, 99438, Bad Berka, Germany.

Copyright

(Copyright © 2006, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s00381-005-1151-3

PMID

15864705

Abstract

RATIONALE: We report on a cerebral infection by Pseudallescheria boydii in a 21-month-old boy after a near-drowning episode. MRI revealed multiple (> 60) intracerebral abscesses. METHODS: The surgical therapy included CSF drainage and microsurgical resection of one abscess for microbiological diagnosis. Antimycotic therapy included terbinafine and intraventricular caspofungin in addition to voriconazole. RESULTS: Systemic side effects of chemotherapy were not observed. After placement of a ventriculoperitoneal shunt, the boy was transferred to a rehabilitation clinic and improved neurologically. After 20 months, MRI documented a continuing remission of the disease. CONCLUSION: Our case proves that an aggressive treatment should be undertaken and can be successful in CNS pseudallescheriasis.

Language: en